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Gstm1 breast cancer

WebDec 1, 1999 · For breast cancer, the GSTM1-null genotype has been found to confer an increased risk in young post-menopausal women , whereas other studies did not find any … Web1 Introduction. Breast cancer is the most common malignant tumor and cause of cancer-related death among women, representing a major health problem worldwide. In …

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WebMar 10, 2024 · Fourteen previous meta-analyses have been published to analyze the polymorphisms of individual GSTM1 present/null, GSTT1 present/null, and GSTP1 … WebIn the current study, we investigated the relationship between the levels of aromatic DNA adducts in breast tissues and polymorphisms of the drug-metabolizing genes cytochrome P4501A1 (CYP1A1), N-acetyltransferase-2 (NAT2), and glutathione S-transferase M1 (GSTM1), in 166 women having breast cancer. christian trostmann https://bryanzerr.com

SCUBE2 Suppresses Breast Tumor Cell Proliferation and Confers a ...

WebNov 1, 2001 · Abstract. The glutathione S-transferase (GST) genes are involved in the metabolism of various carcinogens. Deletion polymorphisms in the GSTM1 and GSTT1 … WebApr 15, 2009 · Abstract. Signal peptide-CUB-epidermal growth factor–like domain-containing protein 2 (SCUBE2), originally identified from the endothelium and several nonendothelial primary cell types, was recently shown to be expressed in invasive breast carcinomas. However, the protein localization and biological significance of SCUBE2 in breast … WebGSTM1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. christian trophies

Clinical significance and biological mechanisms of glutathione S ...

Category:Effects of GSTT1 and GSTM1 polymorphisms in glutathione levels …

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Gstm1 breast cancer

Figure 1: Breast carcinoma-specific DFS of axillary

WebMar 10, 2024 · Background: Fourteen previous meta-analyses have been published to analyze the polymorphisms of individual GSTM1 present/null, GSTT1 present/null, and GSTP1 IIe105Val on breast cancer (BC) risk. However, their meta-analyses did not explore the combined effects of the three genetic polymorphisms on BC risk. In addition, they did … WebPolymorphisms in the glutathione transferase enzymes (GSTs) genes have been associated with susceptibility to develop breast cancer (BC), but few are known regarding its role on this disease prognosis and impact on antioxidant status. This study evaluated the polymorphisms of GSTM1 and GSTT1 genes a …

Gstm1 breast cancer

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WebIn this study 14.28% of cases had at least one family history of cancer, among them 5.72 represented breast cancer, 1.43% represented familial breast cancer plus other types …

WebMar 27, 2024 · Since oral cancer is a global health concern and alcohol and tobacco consumption are major risk factors involved in its carcinogenesis, the aim of this study was to evaluate the Fagerström and AUDIT tests as likely screening tools for oral cancer and their correlation with the expression of CYP1A1, GSTM1, GSTP1, and GSTT1 genes … WebNov 1, 2024 · PurposeDeletion of Glutathione S-Transferase Theta 1 (GSTT1) encoding gene is implicated in breast cancer susceptibility, clinical outcomes, and survival. Contradictory results have been reported in different studies. The present investigation based on a representative Pakistani population evaluated the GSTT1-absent genotype in …

WebSep 19, 2013 · The gene for glutathione-S-transferase (GST) M1 (GSTM1), a member of the GST-superfamily, is widely studied in cancer risk with … WebIn another meta-analysis study, the GSTM1 and GSTP1 polymorphisms (under allelic and dominant model) were found to be associated with increased breast cancer risk Asian population, especially in East Asians, and that the GSTT1 polymorphism might not be associated with breast cancer. 38 These differences between different meta-analyses …

WebSep 20, 2024 · The gel electrophoresis technique was used to detect the genotype for the GSTM1, GSTT1, and GSTP1 genetic variants. GSTM1 genotyping was based on the …

WebCigarette smoking, glutathione-S-transferase M1 and T1 genetic polymorphisms, and breast cancer risk (United States) Francis Ali-Osman 2002, Cancer Causes and Control geothermal energy near meWeb// Jie Ma 1, * , Shao-Liang Zhu 2, * , Yang Liu 3, * , Xiang-Yang Huang 1 and Dan-Ke Su 1 1 Department of Radiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China 2 Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China 3 Department of Radiotherapy, Affiliated Tumor Hospital of … geothermal energy map usaWebGSTM1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … geothermal energy nordicWebEDRN; Data and Resources; Publications; Sensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study. geothermal energy norwayWebJun 11, 2010 · GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer Genet Mol Res . 2010 Jun 11;9(2):1045-53. doi: 10.4238/vol9-2gmr726. geothermal energy labWebSensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study. geothermal energy michiganWebNo correlation was found between GSTM1 null variant and breast cancer risk. Study showed that variant genotype of GSTM1 null polymorphism was associated with an increased risk of fetal growth restriction among mothers who were smokers. Among … christian troubled boys programs