2024 Palbociclib molecular weight

Palbociclib molecular weight

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August undefined, 2024

WebPalbociclib HCl. Molecular Formula CHClNO. Average mass 483.994 Da. Monoisotopic mass 483.214966 Da. ChemSpider ID 9606535. WebMolecular Weight: 447.53. NACRES: NA.77. Recommended Products. Slide 1 of 10. 1 of 10. Sigma-Aldrich. PZ0199. PD 0332991 isethionate. ≥98% (HPLC) View Price and Availability. …

Palbociclib monohydrochloride CDK TargetMol

WebMolecular Weight: 447.53. NACRES: NA.77. Recommended Products. Slide 1 of 10. 1 of 10. Sigma-Aldrich. PZ0199. PD 0332991 isethionate. ≥98% (HPLC) View Price and … WebMolecular Weight: 447.53. NACRES: NA.77. Recommended Products. Slide 1 of 10. 1 of 10. Sigma-Aldrich. PZ0199. PD 0332991 isethionate. ≥98% (HPLC) View Price and … pop up tent with floor

Product Data Sheet - MedchemExpress.com

WebHowever, the isethionate counterion adds a lot of unnecessary mass to palbociclib (125Da per isethionate unit), making the identification of stable palbociclib salts having a lower molecular weight desirable from the perspective of drug load and efficiency. Weba hydrophilic high-molecular weight material, wherein a mass ratio of the tartaric acid to the palbociclib or the pharmaceutically acceptable salt thereof ranges from 0.5:1 to 5:1, wherein the palbociclib and the tartaric acid are dispersed within the hydrophilic high-molecular weight material; and wherein the palbociclib and tartaric acid are ... WebMolecular Formula: C. 24. H. 29. N. 7. O. 2. Molecular Weight: 447.54 Daltons . CAS Registry: 571190-30-2 . DESCRIPTION Palbociclib is a yellow to orange powder with a pKa of 7.4 … sharon pa deaths

Ibrance (Palbociclib Capsules for Oral Administration): Uses ... - RxList

Palbociclib Desacetyl Impurity - Veeprho

WebApr 13, 2024 · Cytoplasmic expression of low-molecular-weight cyclin E, ... For example, palbociclib-resistant tumor cells with cyclin E overexpression are highly sensitive to CHEK1 inhibitors (Wander et al., 2024), although the molecular basis for this effect is unknown. WebPalbociclib (PD-0332991) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein ... What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol? Enter 197.13 into the Molecular Weight (MW ... sharon pa chamber of commerceWebPalbociclib Desacetyl Impurity or 8-cyclopentyl-5-methyl-2-((5-(piperazine-1-yl)pyridine-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride, is a piperazine pyridopyrimidine derivative and an endocrine-based chemotherapeutic agent and antineoplastic agent that used in the treatment of breast cancer, it acts as to inhibits cell growth and suppresses … sharon pa fire department

"Web英文别名;N-Methyl Palbociclib: CAS号: 571189-51-0: 分子式 Formula: C25H31N7O2: 分子量 Molecular Weight: 461.56: 储藏条件 Storage conditions: storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years) " - Palbociclib molecular weight

Palbociclib molecular weight

Palbociclib - CAS-Number 571190-30-2 - Order from Chemodex

WebJan 3, 2024 · Ibrance capsules for oral administration contain 125 mg, 100 mg, or 75 mg of palbociclib, a kinase inhibitor. The molecular formula for palbociclib is C 24 H 29 N 7 O 2. The molecular weight is 447.54 daltons. WebAn impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. ... Molecular Formula. C14H21BrN4. Molecular Weight. 325.25. Size Price Stock Quantity; 2 mg: $229: In stock: Request another packsize?

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WebPalbociclib-d4, TRC-P139901-10MG, from Stable isotopes. High-quality, certified reference materials, available to purchase online at LGC Standards. WebJan 4, 2024 · Chemsrc provides palbociclib(CAS#:571190-30-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of palbociclib are …

WebFeb 26, 2024 · Intrinsic molecular subtype and efficacy of palbociclib (PAL). (A) Intrinsic subtype distribution of tumors in the PALOMA-3 trial. (B ... CDK4/6 traditionally has been viewed as being required for G1 transition by activating CDK2. 33 High expression of low-molecular-weight CCNE1 assessed by immunohistochemistry has been ... Web4 Approved. Molecular Formula: C24H29N7O2. Molecular Weight: 447.54. ChEMBL Synonyms: PALBOCICLIB PD-0332991. Synonyms From Alternative Forms: PALBOCICLIB …

WebPALBOCICLIB N-FORMYL IMPURITY NJB3FNK33C Other Structure Moieties 1: General Record Details Names 2: Identifiers 3 ... Molecular Weight: 475.5438: Optical Activity: NONE Defined Stereocenters: 0 / 0: E/Z Centers: 0: Charge: 0: SHOW SMILES / InChI. SHOW STEREO... HIDE STEREO... Structure Search; WebPalbociclib is an orally available cyclin-dependent kinase (CDK) ... What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the …

WebChemical Modulators for studying Palbociclib in the research area. ... Molecular Weight: 447.5 g/mol: Purity >98%: Molecular Formula: C 24 H 29 N 7 O 2: CAS: 571190-30-2: …

WebMolecular Formula: C24H29N7O2: Molecular Weight: 447.53: Category: ... Palbociclib Impurity A is related to the parent compound, Palbocicib (P139900) (also known as compound number PD-0332991), which is an experimental drug for the treatment of breast cancer being developed by Pfizer. pop up tent with nettingWebMolecular Weight: 447.54 daltons: Appearance: yellow to orange powder: Solubility: At or below pH 4, palbociclib behaves as a high-solubility compound. Above pH 4, the solubility of the drug substance reduces significantly. It is slightly soluble in dimethyl sulfoxide and dimethylformamide, very slightly soluble in methanol and water. pop up tent with heaterWebMolecular Weight. Product Data; Handling; Safety Information; Details; Specifications Purity ≥98% (HPLC) Identity 1H-NMR Appearance Light-yellow or off-yellow powder, beige Properties Solvents ... Palbociclib is a potent and selective inhibitor of CDK4 (IC50=11nM) and CDK6 (IC50=16nM). sharon pa fire festivalWebPalbociclib (PD 0332991) 571190-30-2 Not Listed Muta 2 (H341) STOT RE. 2 (H373) Aquatic Chronic 2 (H411) 20 - 30 Ingredient CAS Number EU EINECS/ELINCS ... Molecular Weight: Mixture Palbociclib (PD 0332991) Measured 7 Log D 1.11 Physical State: Capsule Cellulose microcrystalline Revision date: 14-Jul-2024 No data available pop up tent with side wallsWebN-Nitroso Palbociclib is an impurity present in Palbociclib, ... Molecular Formula: C24H28N8O3. Molecular Weight: 476.53 g/mol. Parent drug: Palbociclib. IUPAC Name: 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)pyrido[2, 3-d]pyrimidin-7(8H)-one. pop up tent with porchWebVisit ChemicalBook To find more Palbociclib Impurity 155(1899700-50-5) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. You can also browse global suppliers,vendor,prices,Price,manufacturers of Palbociclib Impurity … sharon pa funeral homeWebPalbociclib N-Lactose: Molecular Formula: C36H49N7O12: Molecular Weight: 771.81: Category: Standards; Pharmaceutical/API Drug Impurities/Metabolites; Applications: Palbociclib N-Lactose is an impurity of Palbociclib which is an experimental drug for the treatment of breast cancer being developed by Pfizer. sharon page cynergy