WebA series of expression vectors for Tax (pβMT‐2 Tax) and its mutants (Tax M22 and Tax 703) were described previously. 23, 24 Tax M22 has an amino acid substitution at codons 130 and 131 from Thr‐Leu to Ser‐Ala. Tax 703 has an amino acid substitution at codons 319 and 320 from Leu‐Leu to Arg‐Ser, which is equivalent to mutant M47. WebOct 19, 2024 · Langellier Brent A., Lê-Scherban Félice, Purtle Jonathan (2024), “Funding Quality Pre-Kindergarten Slots with Philadelphia’s New ‘Sugary Drink Tax:’ Simulating Effects of Using an Excise Tax to Address A Social Determinant of Health,” Public Health Nutrition, 20 (13), 2450–8.
XBP-1, a novel human T-lymphotropic virus type 1 (HTLV-1) tax …
WebTax mutant d3 which cannot activate CREB/ATF1, while another M22 mutant which cannot activate NF-kappaB did not, suppressed Fas-mediated apoptosis by inducing c-FLIP … WebSep 10, 2024 · Using several Tax expression constructs, an increase of Tax protein occurred independent of Tax transcripts and independent of the promoter used. Further, Tax and M22 protein expression were strongly enhanced by 12-O-Tetradecanoylphorbol-13-Acetate … east surrey cats protection
HTLV-1 Tax Stabilizes MCL-1 via TRAF6-Dependent K63-Linked ...
WebMar 16, 2012 · The expression vectors for Tax [Tax wild type (WT)] and mutant Tax (Tax M22) have been described previously. 18 Wild-type and mutants miR-146a promoter/luciferase reporter plasmids, miR-146a pro-Luc, were kind gifts from Erik K. Flemington (Tulane Cancer Center, New Orleans, LA). 19 An NF-κB reporter plasmid (κB … Webactivated in various cell lines expressing the wild type viral Tax protein while this induction was minimal upon expression of NF-κB activation-defective TaxM22. Cotransfection of these Tax expression vectors with galectin-1 promoter-driven luciferase constructs confirmed that Tax upregulated galectin-1 promoter activity. WebMar 16, 2007 · As Tax M22 was known to be defective in IKKγ binding (Chu et al, 1999; Harhaj & Sun, 1999; Jin et al, 1999), it is logical to propose that Tax might function as an adaptor, mediating the Tak1–IKK association through binding to both of these cellular signalling components. ... J Virol 73: 738 – 745 CAS PubMed Web of Science ... cumberland perry area technical school