The single cell type atlas
WebLiang et al. report a comprehensive multi-omics single-cell atlas with nearly 400,000 nuclei and 69 cell types in adult human retina. They identify regulatory elements that are specific … WebApr 10, 2024 · Plant leaf intercellular space provides a nutrient-rich and heterogeneous niche for microbes that critically impacts plant health. However, how individual plant cells respond to heterogeneous microbial colonization remains largely elusive. Here, by time-resolved simultaneous single-cell transcriptome and epigenome profiling of plants ( Arabidopsis …
The single cell type atlas
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WebLiver Single Cell Atlas Abstract: The liver is the largest solid organ in the human body and is responsible for a multitude of essential functions for survival. Chronic liver injury affects over 1 billion people worldwide and therapeutic options other than liver transplantation are a critical unmet medical need. WebApr 13, 2024 · Wang, L. et al. Single cell-type transcriptome profiling reveals genes that promote nitrogen fixation in the infected and uninfected cells of legume nodules. Plant Biotechnol. J. 20, 616–618 (2024).
WebSingle-nucleus RNA sequencing revealed cell type– and sex-specific effects of repeated sevoflurane exposure in the hippocampus of neonatal mice. These differential effects of sevoflurane on distinct hippocampal cell populations and signaling pathways provide new insights into the mechanisms of actions of anesthetics in the developing brain. WebOMICS SEARCH. Gene Expression; Cell Type; Transcription Factor; Receptor-Ligand; Colonotype Abundance
WebApr 14, 2024 · Perhaps one of the most revolutionary next generation sequencing technologies is single-cell (SC) transcriptomics, which was recognized by Nature in 2013 … WebApr 14, 2024 · Perhaps one of the most revolutionary next generation sequencing technologies is single-cell (SC) transcriptomics, which was recognized by Nature in 2013 as the method of the year. SC-technologies delve deep into genomics at the single-cell level, revealing previously restricted, valuable information on the identity of single cells, …
WebA single-cell regulatory atlas of the developing human retina. A) Schematic of experimental design. B) Retinal structure schematic. ... It is also important to investigate the cell-type …
WebRecent advances in single-cell genomic analysis of cells and tissues have put systematic, high-resolution and comprehensive reference maps of all human cells within reach. In other words, we can now realistically envision a human cell atlas to serve as a basis for both understanding human health and diagnosing, monitoring, and treating disease. racket\\u0027s 8WebMar 15, 2024 · (A) Integration and analysis of publicly available healthy BM samples to construct the atlas. 145 healthy BM samples were used to build the final atlas with 673,750 cells in 54 cell types. Blood disease samples of acute myeloid leukaemia and multiple myeloma were projected onto the healthy BM atlas to identify disease-specific populations. racket\\u0027s 7xWebApr 11, 2024 · The miracidium infects a snail host, inside which its stem cells generate daughter sporocysts that give rise to human-infective cercariae larvae. We use a combination of single-cell RNA sequencing, in situ hybridisation and image analysis to characterise the miracidia. Each larva comprises ~365 cells and 19 transcriptionally … racket\u0027s 80WebResearchers discover new type of lung cell, critical insights for cystic fibrosis A comprehensive single-cell analysis of airway cells in mice, validated in human tissue, reveals molecular details critical to … dote menu odivelasWebSummary of RNA expression and protein localization based on data generated within the Human Protein Atlas project. Single cell type expression clusteri. The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually ... racket\\u0027s 81WebNov 24, 2024 · An atlas of cCREs in adult human cell types. ... Due to the varying abundance of cell types in each tissue, single-cell assays typically profile different cell types at different sequencing depths. To account for these differences, we adapted peak calling cutoffs to different sequencing depths. Specifically, we choose a cutoff of FDR less than ... racket\u0027s 7zWebSingle Cells from Mouse Brain Cells are acquired from selected brain areas in the adult mouse. Cells are identified for isolation using transgenic mouse lines harboring … racket\\u0027s 7u