Trim37 function
WebApr 11, 2024 · During chronic hepatitis B virus (HBV) infection, hepatic fibrosis is a serious pathological condition caused by virus-induced liver damage. The activation of hepatic stellate cells (HSCs) is a central event in the occurrence and progression of liver fibrosis. Although accumulating evidence has shown that HBV directly stimulates HSC activation, … WebHuman MID1 (midline-1) is a microtubule-associated protein that is postulated to target the catalytic subunit of protein phosphatase 2A for degradation. It binds alpha4 that then recruits the catalytic subunit of protein phosphatase 2A. As a member of the TRIM (tripartite motif) family, MID1 has three consecutive zinc-binding domains—RING (really interesting …
Trim37 function
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WebPrimary Ovarian Insufficiency. Watchlist. (log in to enable) WebOne-stop service from gene synthesis and vector construction to protein expression and purification. Multiple protein expression systems: bacterial, yeast, baculovirus-insect and …
WebJul 1, 2024 · As a transcription factor, p53 functions as a homotetramer and binds to the p53-responsive elements in p53 target genes to transcribe these genes in cells. 12, 13 The p53-responsive element is composed of two decamers separated by a spacer of 0–14 nucleotides: RRRCWWGYYY (spacer) RRRCWWGYYY, where R is a purine, W is A or T, and … WebNov 15, 2024 · In this study, we unveiled a novel function of TRIM37 in regulating nuclear-to-cytoplasmic NF-κB signaling. We found that, upon genotoxic stimulation, TRIM37 rapidly translocated into the nucleus where it interacted directly with TRAF6 to catalyze monoubiquitination of NEMO at K309.
Web× Close. The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. WebMutations in this gene are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. TRIM37 …
WebSep 9, 2024 · Fig. 1: TRIM37 levels determine mitotic outcomes and cancer-specific sensitivity to PLK4 inhibition. a, Still images from time lapse sequences showing …
WebBCL6 function is also impaired by acetylation, which triggers BCL6 dissociation from corepressor complexes (Bereshchenko et al., 2002). Interestingly, acetylation has a negative effect on BCL6 activity while it positively affects the function of TP53, one of the well-characterized BCL6 targets, suggesting a coordinated action between functional silencing … ecfmg name changeWebShumin Dong,1 Xueqin Pang,2 Haijun Sun,3 Chunluan Yuan,4 Chuanyong Mu,5 Shiying Zheng6 1Department of Thoracic Surgery, The First Affiliated Hospital of... ecfmg moonlightingWebFeb 26, 2024 · The absence of the TRIM37 protein induces the formation of ... The scientific literature shows that development of this disease is associated with the lack of function of a gene known as TRIM37. ecfmg newsWebBray, Global cancer statistics 2024: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, Ca - Cancer J. Clin., № 68, с. 394 complications of collagen injectionsWebNov 1, 2024 · Tripartite motif 37 (TRIM37), a member of the TRIM protein family, was involved in the tumorigenesis of several types of cancer. However, the expression pattern … complications of colonoscopy nhsecfmg medical school directoryWebOct 13, 2024 · TRIMs play vital roles in immune regulation and development and the changes in the function/expression of TRIM proteins which are associated with cancer. ... Wen-Zhong H. Knockdown of TRIM37 suppresses the proliferation, migration and invasion of glioma cells through the inactivation of PI3K/Akt signaling pathway. Biomed ... complications of congenital syphilis